Cobalt Oxide Nanoparticles: Behavior towards Intact and Impaired Human Skin and Keratinocytes Toxicity

Cobalt Oxide Nanoparticles: Behavior towards Intact and Impaired Human Skin and Keratinocytes Toxicity

Skin absorption and toxicity on keratinocytes of cobalt oxide nanoparticles (Co3O4NPs) have been investigated. Co3O4NPs are commonly used in industrial products and biomedicine. There is evidence that these nanoparticles can cause membrane damage and genotoxicity in vitro, but no data are available on their skin absorption and cytotoxicity on keratinocytes. Two independent 24 h in vitro experim...

Cobalt Oxide Nanoparticles: Characterization and its Electrocatalytic Activity towards Nitrobenzene†

Cobalt oxide (Co3O4) nanoparticles were successfully prepared by thermal decomposition of cobalt hydroxide synthesized from cobalt acetate, ammonium hydroxide and 10% glycerol. The cobalt oxide nanoparticles calcined at 450 °C were characterized by using XRD. The XRD confirms the crystallinity and crystal structure of the sample. It also shows that the diffraction peak are broadened which revea...

In vitro Co-Culture of Human Skin Keratinocytes and Fibroblasts on a Biocompatible and Biodegradable Scaffold

Background: Extensive full-thickness burns require replacement of both epidermis and dermis. In designing skin replacements, the goal has been to re-create this model and make a product which has both essential components. Methods: In the present study, we developed procedures for establishing confluent, stratified layers of cultured human keratinocytes on the surface of modified collagen-chito...

Isolation and in vitro cultivation of human skin Keratinocytes and preparation of epidermal sheet

Effect of nitric oxide on skin blood flow of intact and morphine- dependent rats

Introduction: The relation between morphine and nitric oxide release has been shown. Due to important role of nitric oxide in regulation of skin blood flow, the aim of this study was to investigate the effect of nitric oxide synthase inhibitor (L-NAME) and nitric oxide synthesis precursor (L-arginine) on skin blood flow of intact and morphine-dependent rats. Methods: Skin blood flow of hind pa...